Vertebral compression Fracture Risk in Spinal Metastases Patients Following Stereotactic Body Radiotherapy Using Quantitative Imaging Data and Machine Learning

Vertebral compression fractures (VCFs) occur in approximately 14% of patients with spinal metastases following treatment with Stereotactic Body Radiotherapy (SBRT). The Spinal Instability Neoplastic Score (SINS) is the current clinical standard for assessing potential mechanical instability in these patients; however, it has several limitations such as it is manually assessed, has an inconsistent relationship with fracture risk and is only …