Intimate partner violence, which is a violation of human rights, is defined as any behavior within an intimate relationship or ex-relationship that causes physical, psychological, or sexual harm, including physical aggression, psychological violence (such as intimidation, constant humiliation), controlling behaviors (such as restricting access to services), and sexual violence. Intimate partner violence is present in all societies, with over a 25% global lifetime prevalence in women. Although intimate partner violence can occur in any intimate relationship, it is a gendered problem that disproportionately affects women and gender and sexual minorities. Although usually less severe than in women, intimate partner violence experienced by men also increases the risk of health problems and injuries. Although injury is the most obvious clinical manifestation of intimate partner violence, most people who experience intimate partner violence do not present to health care providers with signs of obvious trauma but rather with a constellation of overlapping physical and mental health problems. These conditions may persist even when the abuse ends—particularly chronic pain, gynecologic problems, anxiety, depression, and post-traumatic stress disorder. Universal screening for intimate partner violence is not recommended in health care settings, but clinicians should have a low threshold for asking about abuse and should know how to respond appropriately and safely, including how to facilitate referral to a specialist resource that can offer advocacy and further support. Women survivors of intimate partner violence benefit from advocacy and from trauma-informed psychological treatment.