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Myocardial autophagy as a compensatory response to...
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Myocardial autophagy as a compensatory response to Doxorubicin-induced cardiotoxicity

Abstract

Doxorubicin (Doxo) is an anthracycline antibiotic commonly used in the treatment of a wide range of cancers. Doxo is known for its cumulative dose-dependent cardiotoxicity leading to dilated cardiomyopathy, congestive heart failure and death. To date the precise molecular events contributing to these adverse reactions are not fully understood. Autophagy is a catabolic process, tightly regulated, involved in the recycling of cytoplasmic …

Authors

Dimitrakis P; Konecny F; Zuppinger C; von Harsdorf R

Publication Date

August 4, 2016

DOI

10.7490/f1000research.1112778.1

Associated Experts

Filip Konecny

Lecturer (Adjunct), Faculty of Health Sciences
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