Dual admittance catheter-derived biventricular...

Dual admittance catheter-derived biventricular pressure-volume analysis in swine: comparison with contrast-enhanced computed tomography during transient pressure overload

Abstract

We have compared biventricular Pressure-Volume Analysis in Swine with Contrast-Enhanced Computed Tomography During Transient Pressure Overload. Pressure overload was induced by 60-minute intravenous infusion of phenylephrine (PE; 300 ug/min). Biventricular PV analysis provided reasonably accurate measurements of ventricular volumes compared with contrast-enhanced cardiac multi-detector computed tomography (MDCT). Employing this approach during transient PE infusion demonstrated persistent chamber dilatation and systolic dysfunction in the LV, but not RV, consistent with stretch-induced stunning caused by an acute elevation in preload.

Authors

Konecny F; Smith C; Techiryan G; Canty Jr. JM; Weil BR

Publication Date

April 14, 2019

DOI

10.7490/f1000research.1116595.1

Associated Experts

Filip Konecny

Lecturer (Adjunct), Faculty of Health Sciences

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