Journal article
Exploring Neuroinflammation and Its Role in Postoperative Cognitive Dysfunction Following Spine Surgery.
Abstract
: Background: Progress in spine surgery has significantly improved the safety of proce-dures for older patients with disabling spine disease. However, postoperative cognitive dysfunction (POCD) remain a concern due to their link with poorer outcomes and higher long-term care risk. This study aimed to determine if pro-neuroinflammatory states accelerate neurodegeneration, contributing to POCD development, and explore whether specific biomarkers …
Authors
Ruhnau J; Müller J; Nowak S; Strack S; Sperlich D; Pohl A; Dilz J; Rehberg S; Usichenko T; Hahnenkamp K
Journal
Gerontology, , , pp. 1–20
Publisher
Karger Publishers
Publication Date
October 20, 2025
DOI
10.1159/000548923
ISSN
0304-324X