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Comparison of Pretreatment Strategies for cT2cN0...
Journal article

Comparison of Pretreatment Strategies for cT2cN0 Staged Adenocarcinoma of the Esophagus and the Gastroesophageal Junction: A European High-Volume Center Cohort Analysis

Abstract

BackgroundAfter the ESOPEC trial showed a survival benefit for fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT)-treated adenocarcinomas of the esophagus (EAC) and the gastroesophageal junction (GEJ) compared with Chemoradiotherapy for Oesophageal Cancer Followed by Surgery Study (CROSS), a European, high-volume center study for stage cT2cN0 EAC and GEJ was undertaken, as it has been published that a third of these patients are …

Authors

Wirsik NM; Schmidt T; Kooij CD; Dempster N; Crnovrsanin N; Donlon NE; Uzun E; Bhanot K; Nienhüser H; Polette D

Journal

Annals of Surgical Oncology, Vol. 32, No. 13, pp. 10128–10136

Publisher

Springer Nature

Publication Date

12 2025

DOI

10.1245/s10434-025-18311-8

ISSN

1068-9265