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Pharmacological management of upper...
Journal article

Pharmacological management of upper gastrointestinal Crohn’s disease: a systematic review

Abstract

BACKGROUND: Upper gastrointestinal Crohn's disease (UGICD) is an uncommon phenotype with limited management guidelines. We reviewed evidence on the safety and efficacy of pharmacological interventions for UGICD. METHODS: We searched MEDLINE, Embase, and Cochrane CENTRAL (1990-2025) for randomized controlled trials (RCTs) and comparative observational studies evaluating pharmacological or dietary interventions for UGICD, including esophagus to …

Authors

Chatto M; Alaskar D; Ma C; Yuan Y; Vuyyuru SK; Bessissow T; Narula N; Danese S; Peyrin-Biroulet L; Singh S

Journal

Journal of Crohn's and Colitis, Vol. 19, No. 10,

Publisher

Oxford University Press (OUP)

Publication Date

November 8, 2025

DOI

10.1093/ecco-jcc/jjaf187

ISSN

1197-4982