CAR-T for management of R/R PTLD following lung transplant: A multi-center retrospective study

Post-transplant lymphoproliferative disorder (PTLD) is a rare malignancy following solid organ transplantation (SOT), with lung transplant recipients experiencing disproportionately high rates of progression and mortality. While CD19-directed chimeric antigen receptor T-cell (CAR-T) therapy has demonstrated efficacy in relapsed/refractory (R/R) B-cell lymphoma, its role in PTLD remains underexplored, particularly in lung SOT. We present a …