Comparative analysis of hsp16 and hsp70 heat shock protein families in Caenorhabditis nematodes

Abstract

The heat shock response (HSR), driven by molecular chaperons, is a key defense mechanism against proteotoxic stress. In nematodes, the hsp16 family and hsp70 family play central roles in the HSR, but their evolutionary conservation and expression patterns remain poorly understood. Here, we performed phylogenetic, genomic, and transcriptomic analyses of hsp16 and hsp70 genes in Caenorhabditis elegans and C. briggsae, and other related nematodes. …

Authors

Berg WVD; Bhullar H; Gupta BP

Publication date

October 14, 2025

DOI

10.1101/2025.10.13.682214

Preprint server

Cold Spring Harbor Laboratory

Associated Experts

Bhagwati Gupta

Professor, Faculty of Science

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