Difficulties related to sensory processing in Autism Spectrum Disorder (ASD) and attention/deficit-hyperactivity disorder (ADHD) can manifest within multiple modalities and impact daily functioning. We examined the factor structure of the Short Sensory Profile in ASD and ADHD (N=517). A seven-factor structure held for ASD and ADHD however, differences were found in responses to the sensory measure. At the subscale level, a two-factor structure emerged in ASD, while a single-factor solution emerged in ADHD. Although there are differences in the way those with ASD and ADHD process sensory information, a single inventory can be used to describe processing patterns in both groups. Establishing the shared and non-shared features of sensory processing may have the potential to inform more targeted clinical approaches.