Journal article
Barrett’s Oesophagus Surveillance versus endoscopy at need Study (BOSS): a randomized controlled trial
Abstract
BACKGROUND & AIMS: Barrett's esophagus (BE) is a precursor lesion for esophageal adenocarcinoma (EAC). Surveillance endoscopy aims to detect early malignant progression; although widely practiced, it has not previously been tested in a randomized trial.
METHODS: BOSS (Barrett's Oesophagus Surveillance Versus Endoscopy at Need Study) was a randomized controlled trial at 109 centers in the United Kingdom. Patients with BE were randomized to …
Authors
Old O; Jankowski J; Attwood S; Stokes C; Kendall C; Rasdell C; Zimmermann A; Massa MS; Love S; Sanders S
Journal
Gastroenterology, Vol. 169, No. 6, pp. 1233–1243.e8
Publisher
Elsevier
Publication Date
November 2025
DOI
10.1053/j.gastro.2025.03.021
ISSN
0016-5085