Journal article
Sex- and brain region-specific alterations in brain volume in germ-free mice
Abstract
Several lines of evidence demonstrate that microbiota influence brain development. Using high-resolution ex vivo magnetic resonance imaging (MRI), this study examined the impact of microbiota status on brain volume and revealed microbiota-related differences that were sex and brain region dependent. Cortical and hippocampal regions demonstrate increased sensitivity to microbiota status during the first 5 weeks of postnatal life, effects that …
Authors
Thompson SL; Ellegood J; Bowdish DME; Lerch JP; Foster JA
Journal
iScience, Vol. 27, No. 12,
Publisher
Elsevier
Publication Date
December 2024
DOI
10.1016/j.isci.2024.111429
ISSN
2589-0042