Preprint
Methotrexate and Tumor Necrosis Factor Inhibitors Independently Decrease Neutralizing Antibodies after SARS-CoV-2 Vaccination: Updated Results from the SUCCEED Study
Abstract
Objective: SARS-CoV-2 remains the third most common cause of death in North America. We studied methotrexate and tumor necrosis factor inhibitor (TNFi) effects on neutralization responses post-COVID vaccination, in immune-mediated inflammatory disease(IMID). Methods: Prospective data and sera on adults with inflammatory bowel disease (IBD), rheumatoid arthritis (RA), spondyloarthritis (SpA), psoriatic arthritis (PsA) and systemic lupus (SLE) …
Authors
Hitchon CA; Bowdish DME; Boire G; Fortin PR; Flamand L; Chandran V; Dayam RM; Gingras A-C; Card CM; Colmegna I
DOI
10.20944/preprints202408.1998.v1
Preprint server
Preprints.org