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Liver‐on‐a‐Chip Integrated with Label‐Free Optical...
Journal article

Liver‐on‐a‐Chip Integrated with Label‐Free Optical Biosensors for Rapid and Continuous Monitoring of Drug‐Induced Toxicity

Abstract

Drug toxicity assays using conventional 2D static cultures and animal studies have limitations preventing the translation of potential drugs to the clinic. The recent development of organs-on-a-chip platforms provides promising alternatives for drug toxicity/screening assays. However, most studies conducted with these platforms only utilize single endpoint results, which do not provide real-time/ near real-time information. Here, a versatile …

Authors

Yang J; Khorsandi D; Trabucco L; Ahmed M; Khademhosseini A; Dokmeci MR; Ye JY; Jucaud V

Journal

Small, Vol. 20, No. 48,

Publisher

Wiley

Publication Date

November 2024

DOI

10.1002/smll.202403560

ISSN

1613-6810