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European Headache Federation (EHF) critical...
Journal article

European Headache Federation (EHF) critical re-appraisal and meta-analysis of oral drugs in migraine prevention—part 2: flunarizine

Abstract

ObjectiveNovel disease-specific and mechanism-based treatments sharing good evidence of efficacy for migraine have been recently marketed. However, reimbursement by insurers depends on treatment failure with classic anti-migraine drugs. In this systematic review and meta-analysis, we aimed to identify and rate the evidence for efficacy of flunarizine, a repurposed, first- or second-line treatment for migraine prophylaxis.MethodsA systematic …

Authors

Deligianni CI; Sacco S; Ekizoglu E; Uluduz D; Gil-Gouveia R; MaassenVanDenBrink A; Ornello R; Sanchez-del-Rio M; Reuter U; Versijpt J

Journal

The Journal of Headache and Pain, Vol. 24, No. 1,

Publisher

Springer Nature

DOI

10.1186/s10194-023-01657-3

ISSN

1129-2369