The Use of Rifampin in Total Joint Arthroplasty: A Systematic Review and Meta-Analysis of Comparative Studies

Abstract

BACKGROUND: Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA). Rifampin is an antibiotic with the ability to penetrate bacterial biofilms, and thus has been considered as a potentially important adjunct in the prevention and treatment of PJI. The aim of this systematic review is to evaluate and summarize the use of rifampin in TJA, particularly in the context of PJI. METHODS: A literature …

Authors

Kruse CC; Ekhtiari S; Oral I; Selznick A; Mundi R; Chaudhry H; Pincus D; Wolfstadt J; Kandel CE

Journal

The Journal of Arthroplasty, Vol. 37, No. 8, pp. 1650–1657

Publisher

Elsevier

Publication Date

8 2022

DOI

10.1016/j.arth.2022.03.072

ISSN

0883-5403

Associated Experts

Seper Ekhtiari

Assistant Clinical Professor, Faculty of Health Sciences

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