Preprint
99m Tc-Labelled Photoacoustic Imaging Probe for Detection of Bacterial Infection
Abstract
The development of a non-invasive infection-specific diagnostic probe holds the potential to vastly improve early-stage detection of infection, enabling precise therapeutic intervention and potentially reducing the incidence of antibiotic resistance. Towards this goal, a commercially available bacteria-targeting Zinc (II)-dipicolylamine (ZnDPA)-derived fluorophore, PSVue794, was assessed as a photoacoustic (PA) imaging probe (PIP). A …
Authors
Swann R; Hernández-Valdés D; Silva LR; Marfatia YM; El-Zaria ME; Genady AR; Kwiecien JM; Valliant JF; Sadeghi S
DOI
10.21203/rs.3.rs-4178635/v1
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