Journal article
Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review
Abstract
BackgroundIslet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify heterogeneity before, at, and after T1D diagnosis, and in response to disease-modifying therapies.MethodsWe systematically reviewed PubMed and EMBASE databases (6/14/2022) assessing 10 years of original research examining relationships …
Authors
Felton JL; Redondo MJ; Oram RA; Speake C; Long SA; Onengut-Gumuscu S; Rich SS; Monaco GSF; Harris-Kawano A; Perez D
Journal
Communications Medicine, Vol. 4, No. 1,
Publisher
Springer Nature
DOI
10.1038/s43856-024-00478-y
ISSN
2730-664X