Journal article
Abstract 4798: MRI screening for brain metastases (BrM) versus SYMptom-directed brain imaging for patients with triple negative (TN) or HER2+ metastatic breast cancer (MBC): An ad-hoc interim analysis of a randomized phase II pilot study
Abstract
Abstract Background: Patients with HER2+ or TN MBC are at high risk of developing BrM, but the role of MRI screening for early detection of asymptomatic BrM has not yet been established. Methods: We conducted a multicentre phase II pilot study, which randomized patients with TN or HER2+ MBC to 1 year of BrM screening (contrast enhanced brain MRI at baseline, 4, 8, and 12 months) versus a control arm of symptom directed brain imaging (MRI only …
Authors
Jerzak KJ; Shum M; Pond G; Freedman O; Chandhoke G; Conrad T; Brastianos P; Stanisz G; Sahgal A; Warner E
Journal
Cancer Research, Vol. 84, No. 6_Supplement, pp. 4798–4798
Publisher
American Association for Cancer Research (AACR)
Publication Date
March 22, 2024
DOI
10.1158/1538-7445.am2024-4798
ISSN
0008-5472