Journal article
MRI index of glymphatic system mediates the influence of locus coeruleus on cognition in Parkinson's disease
Abstract
INTRODUCTION: Although locus coeruleus (LC) has been demonstrated to play a critical role in the cognitive function of Parkinson's disease (PD), the underlying mechanism has not been elucidated. The objective was to investigate the relationship among LC degeneration, cognitive performance, and the glymphatic function in PD.
METHODS: In this retrospective study, 71 PD subjects (21 with normal cognition; 29 with cognitive impairment (PD-MCI); 21 …
Authors
Wang X; Huang P; Haacke EM; Wu P; Zhang X; Zhang H; Cheng Z; Tang R; Liu F; Liu Y
Journal
Parkinsonism & Related Disorders, Vol. 123, ,
Publisher
Elsevier
Publication Date
6 2024
DOI
10.1016/j.parkreldis.2024.106558
ISSN
1353-8020