Journal article
A Systematic Review of Sex-Specific Reporting in Heart Failure Clinical Trials Trial Flow and Results
Abstract
Background: Females are historically underenrolled in heart failure (HF) randomized controlled trials (RCTs) relative to disease prevalence. Sex differences in trial flow, including withdrawals and losses to follow up, may further limit the generalizability of results.
Objectives: This study aimed to assess the frequency of sex-specific reporting of trial flow, treatment efficacy, and adverse events in HF RCTs.
Authors
Au M; Whitelaw S; Khan MS; Mamas MA; Mbuagbaw L; Mulvagh SL; Voors AA; Van Spall HGC
Journal
JACC Advances, Vol. 1, No. 4,
Publisher
Elsevier
Publication Date
October 2022
DOI
10.1016/j.jacadv.2022.100079
ISSN
2772-963X