Journal article
Concurrent Use of Statins in Patients Undergoing Curative Intent Treatment for Triple Negative Breast Cancer: A Systematic Review and Meta-Analysis
Abstract
Pre-clinical studies in triple negative breast cancer (TNBC) suggest that statins may inhibit cell proliferation, promote cell-cycle arrest, induce apoptosis, change the tumor microenvironment, and improve effectiveness of other therapies. Observational studies have demonstrated variable effects from statin therapy on oncologic outcomes in these patients. As such, we aimed to pool previous data via a systematic review and meta-analysis to …
Authors
McKechnie T; Brown Z; Lovrics O; Yang S; Kazi T; Eskicioglu C; Parvez E
Journal
Clinical Breast Cancer, Vol. 24, No. 3, pp. e103–e115
Publisher
Elsevier
Publication Date
April 2024
DOI
10.1016/j.clbc.2023.12.001
ISSN
1526-8209