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Analgesia and sedation strategies in neonates...
Journal article

Analgesia and sedation strategies in neonates undergoing whole-body therapeutic hypothermia: A scoping review

Abstract

BACKGROUND: Therapeutic hypothermia (TH) is a widely practiced neuroprotective strategy for neonates with hypoxic-ischemic encephalopathy. Induced hypothermia is associated with shivering, cold pain, agitation, and distress. OBJECTIVE: This scoping review determines the breadth of research undertaken for pain and stress management in neonates undergoing hypothermia therapy, the pharmacokinetics of analgesic and sedative medications during …

Authors

Joshi M; Muneer J; Mbuagbaw L; Goswami I

Journal

PLOS ONE, Vol. 18, No. 12,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0291170

ISSN

1932-6203