A 3D Network of Nanochannels for Possible Ion and Molecule Transit in Mineralizing Bone and Cartilage

During crucial growth stages of vertebrate long bones, calcified cartilage beneath the growth plate is anchored to bone by a third mineralized component, the cement line. Proper skeletal development is contingent on the interplay of these three constituents, yet their mineralization processes and structural interactions are incompletely understood, in part from limited knowledge of their meso‐ and nanoscale features. Herein, focused ion …