Journal article
Thinking small to win big? A critical review on the potential application of extracellular vesicles for biomarker discovery and new therapeutic approaches in pancreatic cancer
Abstract
Pancreatic ductal adenocarcinoma (PDAC) is an extremely deadly form of cancer, with limited progress in 5-year survival rates despite significant research efforts. The main challenges in treating PDAC include difficulties in early detection, and resistance to current therapeutic approaches due to aggressive molecular and microenvironment features. These challenges emphasize the importance of identifying clinically validated biomarkers for early …
Authors
Vahabi M; Comandatore A; Centra C; Blandino G; Morelli L; Giovannetti E
Journal
Seminars in Cancer Biology, Vol. 97, , pp. 50–67
Publisher
Elsevier
Publication Date
December 2023
DOI
10.1016/j.semcancer.2023.11.003
ISSN
1044-579X