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Journal article

Health-Related Quality of Life in Patients with Spinocerebellar Ataxia: a Validation Study of the EQ-5D-3L

Abstract

Although health-related quality of life (HRQoL) has developed into a crucial outcome parameter in clinical research, evidence of the EQ-5D-3L validation performance is lacking in patients with spinocerebellar ataxia (SCA) types 1, 2, 3, and 6. The objective of this study is to assess the acceptability, validity, reliability, and responsiveness of the EQ-5D-3L. For n = 842 predominantly European SCA patients of two longitudinal cohort studies, …

Authors

Buchholz M; Weber N; Rädke A; Faber J; Schmitz-Hübsch T; Jacobi H; Xie F; Klockgether T; Michalowsky B

Journal

The Cerebellum, Vol. 23, No. 3, pp. 1020–1030

Publisher

Springer Nature

Publication Date

6 2024

DOI

10.1007/s12311-023-01597-3

ISSN

1473-4222