Journal article
Effect of Metformin Versus Placebo on New Primary Cancers in Canadian Cancer Trials Group MA.32: A Secondary Analysis of a Phase III Randomized Double-Blind Trial in Early Breast Cancer
Abstract
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned coprimary or secondary analyses are not yet available. Clinical trial updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has already been reported.Metformin has been …
Authors
Goodwin PJ; Chen BE; Gelmon KA; Whelan TJ; Ennis M; Lemieux J; Ligibel JA; Hershman DL; Mayer IA; Hobday TJ
Journal
Journal of Clinical Oncology, Vol. 41, No. 35, pp. 5356–5362
Publisher
American Society of Clinical Oncology (ASCO)
Publication Date
December 10, 2023
DOI
10.1200/jco.23.00296
ISSN
0732-183X