Journal article
Global transcriptome analysis identifies weight regain-induced activation of adaptive immune responses in white adipose tissue of mice
Abstract
Objective:Studies have indicated that weight regain following weight loss predisposes obese individuals to metabolic disorders; however, the molecular mechanism of this potential adverse effect of weight regain is not fully understood. Here we investigated global transcriptome changes and the immune response in mouse white adipose tissue caused by weight regain.Design:We established a diet switch protocol to compare the effects of weight regain …
Authors
Kyung DS; Sung HR; Kim YJ; Kim KD; Cho SY; Choi JH; Lee Y-H; Kim IY; Seong JK
Journal
International Journal of Obesity, Vol. 42, No. 4, pp. 755–764
Publisher
Springer Nature
Publication Date
4 2018
DOI
10.1038/ijo.2017.297
ISSN
0307-0565