Journal article
Oligoribonucleotide Synthesis. VIII. Insertion of Terminal 5-Phosphate Groupings
Abstract
General oligoribonucleotide synthesis using phosphotriester protection has been extended to allow insertion of terminal 5′-phosphates. Selective removal of 5′-triphenylmethoxyacetyl groups allow phosphorylation by TPS-activated mono-2,2,2-trichloroethylphosphate on protected oligomers.
Authors
Neilson T; Deugau KV; England TE; Werstiuk ES
Journal
Canadian Journal of Chemistry, Vol. 53, No. 7, pp. 1093–1098
Publisher
Canadian Science Publishing
Publication Date
April 1, 1975
DOI
10.1139/v75-152
ISSN
0008-4042