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Characteristics of research-focused human islet...
Journal article

Characteristics of research-focused human islet preparations from organ donors with type 2 diabetes

Abstract

Type 2 diabetes mellitus (T2D) affects 463 million individuals worldwide. β-cell dysfunction and relatively inadequate β-cell mass has been implicated in the pathogenesis of T2D. Primary human islets from T2D patients can reveal the islet dysfunction and the underlying mechanisms and thus have become valued resources for diabetes research. Our center (Human Islet Resource Center, China) has prepared a number of batches of human islets from T2D …

Authors

Liang R; Sun P; Cai X; Liu T; Wang L; Liu N; Ding X; Zhang B; Liu Z; Zou J

Journal

Islets, Vol. 15, No. 1,

Publisher

Taylor & Francis

Publication Date

December 31, 2023

DOI

10.1080/19382014.2023.2219104

ISSN

1938-2014