Journal article
The current role of Tofacitinib in acute severe ulcerative colitis in adult patients: A systematic review
Abstract
BACKGROUND: Despite rescue therapy, acute severe ulcerative colitis (ASUC) is associated with a high risk of colectomy, while treatment options remain limited. Tofacitinib, a rapidly acting Janus Kinase (JAK) inhibitor, is gaining ground as an effective alternative treatment option for the management of acute severe ulcerative colitis, which may prevent emergency colectomy.
METHODS: A systematic literature search of PubMed and Embase was …
Authors
Mpakogiannis K; Fousekis FS; Christodoulou DK; Katsanos KH; Narula N
Journal
Digestive and Liver Disease, Vol. 55, No. 10, pp. 1311–1317
Publisher
Elsevier
Publication Date
October 2023
DOI
10.1016/j.dld.2023.05.021
ISSN
1590-8658