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Reductions in Bone Mineral Density Are Apparent...
Journal article

Reductions in Bone Mineral Density Are Apparent Early in Children With Prevalent Osteonecrosis Lesions Following Leukemia Therapy

Abstract

Osteonecrosis (ON) is a serious complication of childhood acute lymphoblastic leukemia. We determined the prevalence of osteonecrotic lesions in our patient population by a one-time multisite magnetic resonance imaging (MRI) more than 1 year following leukemia therapy. MRI findings were evaluated in relationship to clinical factors (including longitudinal changes in bone mineral density [BMD]). Eighty-six children enrolled in the Steroid …

Authors

Halton JM; Ma J; Babyn P; Matzinger MA; Kaste SC; Scharke M; Fernandez CV; Miettunen P; Ho J; Alos N

Journal

Journal of Bone and Mineral Research, Vol. 38, No. 8, pp. 1104–1115

Publisher

Oxford University Press (OUP)

Publication Date

August 2023

DOI

10.1002/jbmr.4870

ISSN

0884-0431