Integrated Analysis of Blood and Urine Biomarkers to Identify Acute Kidney Injury Subphenotypes and Associations With Long-term Outcomes

Abstract

RATIONALE & OBJECTIVE: Acute kidney injury (AKI) is a heterogeneous clinical syndrome with varying causes, pathophysiology, and outcomes. We incorporated plasma and urine biomarker measurements to identify AKI subgroups (subphenotypes) more tightly linked to underlying pathophysiology and long-term clinical outcomes. STUDY DESIGN: Multicenter cohort study.

Authors

Bhatraju PK; Prince DK; Mansour S; Ikizler TA; Siew ED; Chinchilli VM; Garg AX; Go AS; Kaufman JS; Kimmel PL

Journal

American Journal of Kidney Diseases, Vol. 82, No. 3, pp. 311–321.e1

Publisher

Elsevier

Publication Date

September 2023

DOI

10.1053/j.ajkd.2023.01.449

ISSN

0272-6386

Associated Experts

Amit Garg

Assistant Professor (Part-Time), Faculty of Health Sciences

Visit profile

Labels