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Randomised controlled trials of antihypertensive...
Journal article

Randomised controlled trials of antihypertensive therapy: does exclusion of orthostatic hypotension alter treatment effect? A systematic review and meta-analysis

Abstract

BACKGROUND AND PURPOSE: Management of antihypertensive therapy is challenging in patients with symptomatic orthostatic hypotension, a population often excluded from randomised controlled trials of antihypertensive therapy. In this systematic review and meta-analysis, we sought to determine whether the association of antihypertensive therapy and adverse events (e.g. falls, syncope), differed among trials that included or excluded patients with …

Authors

Reddin C; Murphy R; Hanrahan C; Loughlin E; Ferguson J; Judge C; Waters R; Canavan M; Kenny RA; O’Donnell M

Journal

Age and Ageing, Vol. 52, No. 4,

Publisher

Oxford University Press (OUP)

Publication Date

April 1, 2023

DOI

10.1093/ageing/afad044

ISSN

0002-0729