Preprint
PRY-1/AXIN signaling regulates lipid metabolism in Caenorhabditis elegans
Abstract
SUMMARY The nematode Caenorhabditis elegans is a leading animal model to study how signaling pathway components function in conserved biological processes. Here, we describe the role of an Axin family member, pry-1 , in lipid metabolism. As a central component of the canonical Wnt signaling pathway, pry-1 acts as a scaffold to multiprotein destruction complex that negatively regulates the expression of Wnt target genes. A genome-wide …
Authors
Ranawade A; Mallick A; Gupta BP
DOI
10.1101/289462
Preprint server
bioRxiv