Journal article
Piperacillin-Tazobactam Compared With Cefoxitin as Antimicrobial Prophylaxis for Pancreatoduodenectomy
Abstract
Importance: Despite improvements in perioperative mortality, the incidence of postoperative surgical site infection (SSI) remains high after pancreatoduodenectomy. The effect of broad-spectrum antimicrobial surgical prophylaxis in reducing SSI is poorly understood.
Objective: To define the effect of broad-spectrum perioperative antimicrobial prophylaxis on postoperative SSI incidence compared with standard care antibiotics.
Authors
D’Angelica MI; Ellis RJ; Liu JB; Brajcich BC; Gönen M; Thompson VM; Cohen ME; Seo SK; Zabor EC; Babicky ML
Journal
JAMA: The Journal of the American Medical Association, Vol. 329, No. 18, pp. 1579–1588
Publisher
American Medical Association (AMA)
Publication Date
May 9, 2023
DOI
10.1001/jama.2023.5728
ISSN
0098-7484