Preprint
Intraluminal Prucalopride Increases Propulsive Motor Activities in the Human Colon
Abstract
ABSTRACT Background Luminal application of 5-HT 4 receptor agonists can increase peristalsis in the guinea pig, mouse, rat and rabbit colon. Our aim in the present study was to test the effects of intraluminal prucalopride on motor patterns in the human colon. Methods Colonic motor patterns were studied in vivo in a healthy volunteer using High-Resolution Colonic Manometry (HRCM) with an 84-sensor water perfused catheter with 1cm spacing. …
Authors
Shokrollahi M; Wang X-Y; Milkova N; Huizinga JD; Chen J-H
DOI
10.1101/2020.05.24.20111930
Preprint server
medRxiv