Preprint
Specialized and shared functions of diguanylate cyclases and phosphodiesterases in Streptomyces development
Abstract
Abstract Levels of the second messenger bis-3’-5’-cyclic di-guanosinemonophosphate (c-di-GMP) determine when Streptomyces initiate sporulation to survive under adverse conditions. c-di-GMP signals are integrated into the genetic differentiation network by the regulator BldD and the sigma factor σ WhiG . However, functions of the development-specific c-di-GMP diguanylate cyclases (DGCs) CdgB and CdgC, and the phosphodiesterases (PDEs) RmdA and …
Authors
Haist J; Neumann SA; Al-Bassam MM; Lindenberg S; Elliot MA; Tschowri N
DOI
10.1101/2020.04.24.060822
Preprint server
bioRxiv