Preprint
Mouse models of immune dysfunction: Their neuroanatomical differences reflect their anxiety-behavioural phenotype
Abstract
Abstract
Extensive evidence supports the role of the immune system in modulating brain function and behaviour. However, past studies have revealed striking heterogeneity in behavioural phenotypes produced from immune system dysfunction. Using magnetic resonance imaging (MRI), we studied the neuroanatomical differences among 11 distinct genetically-modified mouse lines (n=371), each deficient in a different element of the immune …
Authors
Fernandes DJ; Spring S; Corre C; Tu A; Qiu LR; Hammill C; Vousden DA; Noakes TLS; Nieman BJ; Bowdish DME
DOI
10.1101/2021.06.14.448406
Preprint server
bioRxiv