Chapter
Uremic Neuropathy
Abstract
Between 60% and 100% of patients with uremia have signs and symptoms of uremic neuropathy. Uremia can lead to the accumulation of guanidino compounds, creatine, creatol, methylglyoxal, guanidine, potassium and hyperparathyroidism, all of which are potentially nephrotoxic. Cross talk between the kidney and brain via anatomic, vasoregulatory, humoral and non humoral bi-directional pathways, uremia triggers the development of central and …
Authors
Arekapudi A; Smith DI
Book title
Pathogenesis of Neuropathic Pain
Pagination
pp. 189-211
Publisher
Springer Nature
Publication Date
2022
DOI
10.1007/978-3-030-91455-4_10