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Quality by design and techno-economic modelling of...
Chapter

Quality by design and techno-economic modelling of RNA vaccine production for pandemic-response

Abstract

Vaccine production platform technologies have played a crucial role in rapidly developing and manufacturing vaccines during the COVID-19 pandemic. The role of disease agnostic platform technologies, such as the adenovirus-vectored (AVV), messenger RNA (mRNA), and the newer self-amplifying RNA (saRNA) vaccine platforms is expected to further increase in the future. Here we present modelling tools that can be used to aid the rapid development and …

Authors

Kis Z; Tak K; Ibrahim D; Daniel S; van de Berg D; Papathanasiou MM; Chachuat B; Kontoravdi C; Shah N

Book title

14th International Symposium on Process Systems Engineering

Series

Computer Aided Chemical Engineering

Volume

49

Pagination

pp. 2167-2172

Publisher

Elsevier

Publication Date

2022

DOI

10.1016/b978-0-323-85159-6.50361-4