Journal article
Exosomes derived from mesenchymal stem cells inhibit neointimal hyperplasia by activating the Erk1/2 signalling pathway in rats
Abstract
BackgroundRestenosis is a serious problem in patients who have undergone percutaneous transluminal angioplasty. Endothelial injury resulting from surgery can lead to endothelial dysfunction and neointimal formation by inducing aberrant proliferation and migration of vascular smooth muscle cells. Exosomes secreted by mesenchymal stem cells have been a hot topic in cardioprotective research. However, to date, exosomes derived from mesenchymal …
Authors
Liu Z; Wu C; Zou X; Shen W; Yang J; Zhang X; Hu X; Wang H; Liao Y; Jing T
Journal
Stem Cell Research & Therapy, Vol. 11, No. 1,
Publisher
Springer Nature
Publication Date
December 2020
DOI
10.1186/s13287-020-01676-w
ISSN
1757-6512