Journal article
IL-6 Signal From the Bone Marrow is Required for the Browning of White Adipose Tissue Post Burn Injury
Abstract
The hypermetabolic stress response after burn contributes to multi-organ failure, sepsis, morbidity, and mortality. The cytokine interleukin 6 (IL-6) has been hypothesized to mediate not only white adipose tissue (WAT) browning in burns, but also other hypermetabolic conditions. In addition to its inflammatory effects, IL-6 also acts as a metabolic mediator that affects metabolic tissues. Therefore, we sought to uncover the origin of …
Authors
Abdullahi A; Chen P; Stanojcic M; Sadri A-R; Coburn N; Jeschke MG
Journal
Shock, Vol. 47, No. 1, pp. 33–39
Publisher
Wolters Kluwer
Publication Date
January 2017
DOI
10.1097/shk.0000000000000749
ISSN
1073-2322