Journal article
Propranolol as a modulator of M2b monocytes in severely burned patients
Abstract
A role of immunosuppressive M2 monocytes (IL-12(-)IL-10(+)) on the increased susceptibility of severely burned patients to various opportunistic pathogens has been described. Among M2 monocyte subpopulations, M2b monocytes (IL-17(-)CCL1(+)CXCL13(-)) are predominantly present in the peripheral blood of severely burned patients. In the present study, the rise and fall of M2b monocytes were examined in severely burned patients treated with …
Authors
Kobayashi M; Jeschke MG; Asai A; Kogiso M; Yoshida S; Herndon DN; Suzuki F
Journal
Journal of Leukocyte Biology, Vol. 89, No. 5, pp. 797–803
Publisher
Oxford University Press (OUP)
Publication Date
February 17, 2011
DOI
10.1189/jlb.1010553
ISSN
0741-5400
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdrenergic beta-AntagonistsAdultAntigens, BacterialBurnsCatecholaminesChildChild, PreschoolEnzyme-Linked Immunosorbent AssayFemaleHumansInfantInterleukin-10Interleukin-12Interleukin-17MaleMiddle AgedMonocytesPropranololReceptors, Adrenergic, betaStaphylococcal InfectionsStaphylococcus aureusYoung Adult