Treatment of infection in burns

Infections remain a leading cause of death in burn patients. For patients with burn size greater than 40 % TBSA, 75 % of all deaths are due to infection [1]. Many features unique to burn patients make diagnosis and management of infection especially difficult. Burn injury represents the most extreme endpoint along the spectrum of traumatic injury and as such is associated with profound alterations in host defense mechanisms and immune function. These derangements predispose thermally injured patients to local and systemic invasion by microbial pathogens.