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Hydrogen sulfide is an endogenous stimulator of...
Journal article

Hydrogen sulfide is an endogenous stimulator of angiogenesis

Abstract

The goal of the current study was to investigate the role of exogenous and endogenous hydrogen sulfide (H(2)S) on neovascularization and wound healing in vitro and in vivo. Incubation of endothelial cells (ECs) with H(2)S enhanced their angiogenic potential, evidenced by accelerated cell growth, migration, and capillary morphogenesis on Matrigel. Treatment of chicken chorioallantoic membranes (CAMS) with H(2)S increased vascular length. …

Authors

Papapetropoulos A; Pyriochou A; Altaany Z; Yang G; Marazioti A; Zhou Z; Jeschke MG; Branski LK; Herndon DN; Wang R

Journal

Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 51, pp. 21972–21977

Publisher

Proceedings of the National Academy of Sciences

Publication Date

December 22, 2009

DOI

10.1073/pnas.0908047106

ISSN

0027-8424