Journal article
Alternatively Activated Macrophages Drive Browning of White Adipose Tissue in Burns
Abstract
OBJECTIVE: The aim of this study was to uncover the mediators and mechanistic events that facilitate the browning of white adipose tissue (WAT) in response to burns.
BACKGROUND: In hypermetabolic patients (eg, burns, cancer), the browning of WAT has presented substantial clinical challenges related to cachexia, atherosclerosis, and poor clinical outcomes. Browning of the adipose tissue has recently been found to induce and sustain …
Authors
Abdullahi A; Auger C; Stanojcic M; Patsouris D; Parousis A; Epelman S; Jeschke MG
Journal
Annals of Surgery, Vol. 269, No. 3, pp. 554–563
Publisher
Wolters Kluwer
Publication Date
March 2019
DOI
10.1097/sla.0000000000002465
ISSN
0003-4932