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Thermal Stress Induces Long-Term Remodeling of...
Journal article

Thermal Stress Induces Long-Term Remodeling of Adipose Tissue and Is Associated with Systemic Dysfunction

Abstract

ABSTRACT: Severe burns are characterized by the magnitude and duration of the hypermetabolic response thereafter, and demarcated by the loss of lean body mass and catabolism of fat stores. The aim of the present study was to delineate the temporal and location-specific physiological changes to adipose depots and downstream consequences post-burn in a murine model of thermal injury. C57BL/6 mice were subjected to a 30% total body surface area …

Authors

Knuth CM; Auger C; Chi L; Barayan D; Abdullahi A; Jeschke MG

Journal

Shock, Vol. 56, No. 5, pp. 744–754

Publisher

Wolters Kluwer

Publication Date

November 2021

DOI

10.1097/shk.0000000000001743

ISSN

1073-2322