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Assessment of a multisite standardized biospecimen...
Journal article

Assessment of a multisite standardized biospecimen collection protocol for immune phenotyping in neurodevelopmental disorders

Abstract

Multisite collection and preservation of peripheral blood mononuclear cells (PBMCs) for centralized analysis is an indispensable strategy for large cohort immune phenotyping studies. However, the absence of cross-site standardized protocols introduces unnecessary sample variance. Here we describe the protocol implemented by the Province of Ontario Neurodevelopmental Disorders (POND) Network's immune platform for the multisite collection, …

Authors

Cleary S; Teskey G; Mathews C; Sachachar RJ; Nicolson R; Weksberg R; Anagnostou E; Bowdish DME; Foster JA

Journal

Scientific Reports, Vol. 13, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41598-023-33380-z

ISSN

2045-2322