Journal article
Pilot imaging of the colony stimulating factor 1 receptor in the brains of virally-suppressed individuals with HIV
Abstract
OBJECTIVE: Neuroimmune activation is a putative driver of cognitive impairment in people with HIV (PWH), even in the age of modern antiretroviral therapy. Nevertheless, imaging of the microglial marker, the 18 kDa translocator protein (TSPO), with positron emission tomography (PET) in treated PWH has yielded inconclusive findings. One potential reason for the varied TSPO results is a lack of cell-type specificity of the TSPO target.
DESIGN: [ …
Authors
Rubin LH; Du Y; Sweeney SE; O’Toole R; Harrington CK; Jenkins K; Lesniak WG; Veenhuis RT; Dastgheyb R; Severson J
Journal
AIDS, Vol. 37, No. 9, pp. 1419–1424
Publisher
Wolters Kluwer
Publication Date
July 15, 2023
DOI
10.1097/qad.0000000000003572
ISSN
0269-9370